منابع مشابه
Epilepsy and autism spectrum disorders: are there common developmental mechanisms?
Autistic spectrum disorders (ASD) and epilepsies are heterogeneous disorders that have diverse etiologies and pathophysiologies. The high rate of co-occurrence of these disorders suggest potentially shared underlying mechanisms. A number of well-known genetic disorders share epilepsy and autism as prominent phenotypic features, including tuberous sclerosis, Rett syndrome, and fragile X. In addi...
متن کاملGlioma-Associated Epilepsy
Hughlings Jackson, in the nineteenth century, first noted that epilepsy could be the only clinical manifestation of a primary brain tumour [1] (Figure 1). Among patients with epilepsy, the incidence of brain tumours is about 4% [2] whereas the prevalence of epilepsy among patients with brain tumours is over 30% [3] Seizures will herald the presence of a cerebral glioma in 20-45% of patients [4,...
متن کاملTypes of glioma brain tumors and genetic alterations in signaling pathways in them
Types of glioma brain tumors and genetic alterations in signaling pathways in them Background & Objective: Glioma is a common type of primary brain tumor originating in the glial cells that surrounds and supports neurons in the brain. These tumors arise from three different types of cells that are normally found in the brain: astrocytes, oligodendrocytes, and ependymal cells, accordingly types ...
متن کاملCommon genetic variations in cell cycle and DNA repair pathways associated with pediatric brain tumor susceptibility
Knowledge on the role of genetic polymorphisms in the etiology of pediatric brain tumors (PBTs) is limited. Therefore, we investigated the association between single nucleotide polymorphisms (SNPs), identified by candidate gene-association studies on adult brain tumors, and PBT risk.The study is based on the largest series of PBT cases to date. Saliva DNA from 245 cases and 489 controls, aged 7...
متن کاملGlutamate and tumor-associated epilepsy
For many patients an unexplained seizure is among the earliest symptoms of a growing primary brain tumor. These tumors originate from glial cells or their progenitors in the brain and are often referred to as glioma. In approximately 30% of patients seizures recur spontaneously giving rise to tumor associated epilepsy [1]. While these fits are generally well controlled by antiepileptic medicati...
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ژورنال
عنوان ژورنال: Acta Oncologica
سال: 2009
ISSN: 0284-186X,1651-226X
DOI: 10.1080/02841860903104145